MAC lung disease is an infection caused a group of bacteria called Mycobacterium avium complex (MAC). MAC includes two closely related species, Mycobacterium avium and Mycobacterium intracellulare, and may also be referred to as MAI. MAC is one of a large group of nontuberculous mycobacteria (NTM), and the most common cause of NTM lung disease in the U.S.
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MAC organisms are common in soil and water and are easily inhaled during daily activities. Most of the time they cause no harm, but they can cause infection in groups with certain risk factors. These groups include people living with lung disease such as bronchiectasisandCOPD, and people with a weakened immune system because of an autoimmune disorder or medical treatment such as drugs that compromise immunity. Postmenopausal women and people over 65 years old are also more likely to develop MAC lung disease than the general public.
Key Facts
- MAC infection is a serious condition that can cause damage to the lungs.
- MAC infection is not contagious.
- Common signs and symptoms of MAC lung disease include fatigue, chronic cough, shortness of breath, night sweats, coughing up blood and weight loss. Symptoms may persist or worsen despite being treated for another lung condition.
- MAC lung disease diagnosis includes a clinical exam, a chest x-ray or CT scan and a lab culture of sputum from your lungs.
- MAC lung disease treatment usually involves a combination of antibiotics taken over an extended period of time.
- In addition to lung disease, MAC can also cause an infection that spreads throughout the body, usually in people with advanced AIDS, called disseminated MAC disease, as well as a swelling in the lymph nodes called lymphadenitis that is most common in young children.
For more information about MAC lung disease symptoms, diagnosis and treatment, see our pages on nontuberculous mycobacterial lung disease.
Development of this educational content was supported by a collaborative sponsorship from Insmed Incorporated.
Apple Mac users are being urged to update to macOS Big Sur 11.3, released today, which patches a 'massively bad' vulnerability that could allow malware to bypass layered protections built into the operating system.
The bug was uncovered by security researcher Cedric Owens, who reported it to Apple.
In a long technical blog post, fellow security researcher Patrick Wardle said the bug 'trivially bypasses many core Apple security mechanisms, leaving Mac users at grave risk' and that 'malware authors are already exploiting it in the wild as an 0day'.
The bug was given the common vulnerabilities and exposures (CVE) reference CVE-2021-30657 in Apple security notes, where it is described as a 'logic issue' that could allow 'a malicious application [to] bypass Gatekeeper checks'.
Gatekeeper was introduced in OSX Lion (10.7) as an added layer of protection when users downloaded executables from the internet.
MAC organisms are common in soil and water and are easily inhaled during daily activities. Most of the time they cause no harm, but they can cause infection in groups with certain risk factors. These groups include people living with lung disease such as bronchiectasisandCOPD, and people with a weakened immune system because of an autoimmune disorder or medical treatment such as drugs that compromise immunity. Postmenopausal women and people over 65 years old are also more likely to develop MAC lung disease than the general public.
Key Facts
- MAC infection is a serious condition that can cause damage to the lungs.
- MAC infection is not contagious.
- Common signs and symptoms of MAC lung disease include fatigue, chronic cough, shortness of breath, night sweats, coughing up blood and weight loss. Symptoms may persist or worsen despite being treated for another lung condition.
- MAC lung disease diagnosis includes a clinical exam, a chest x-ray or CT scan and a lab culture of sputum from your lungs.
- MAC lung disease treatment usually involves a combination of antibiotics taken over an extended period of time.
- In addition to lung disease, MAC can also cause an infection that spreads throughout the body, usually in people with advanced AIDS, called disseminated MAC disease, as well as a swelling in the lymph nodes called lymphadenitis that is most common in young children.
For more information about MAC lung disease symptoms, diagnosis and treatment, see our pages on nontuberculous mycobacterial lung disease.
Development of this educational content was supported by a collaborative sponsorship from Insmed Incorporated.
Apple Mac users are being urged to update to macOS Big Sur 11.3, released today, which patches a 'massively bad' vulnerability that could allow malware to bypass layered protections built into the operating system.
The bug was uncovered by security researcher Cedric Owens, who reported it to Apple.
In a long technical blog post, fellow security researcher Patrick Wardle said the bug 'trivially bypasses many core Apple security mechanisms, leaving Mac users at grave risk' and that 'malware authors are already exploiting it in the wild as an 0day'.
The bug was given the common vulnerabilities and exposures (CVE) reference CVE-2021-30657 in Apple security notes, where it is described as a 'logic issue' that could allow 'a malicious application [to] bypass Gatekeeper checks'.
Gatekeeper was introduced in OSX Lion (10.7) as an added layer of protection when users downloaded executables from the internet.
It is one of three such protections built into macOS, all of which are intended to alert users about files downloaded from the internet, and to prevent malware writers from tricking users into infecting their machines.
However, Wardle noted, the bug discovered by Owens allowed an attacker 'to trivially and reliably bypass all of these foundational mitigations', without generating any system prompts that would warn the user something was amiss.
Boring golf mac os. A proof-of-concept showed an app could be disguised as a document and 'allowed to launch with no prompts nor alerts'.
'Since 2007, Apple has sought to protect users from inadvertently infecting themselves if they are tricked into running such malicious code. This is a good thing as sure, users may be naive, but anybody can make mistakes,' Wardle wrote.
'Unfortunately due to subtle logic flaw in macOS, such security mechanisms were proven fully and 100 percent moot, and as such we're basically back to square one.
'We started with an unsigned, unnotarised, script-based proof-of-concept application that could trivially and reliably sidestep all of macOS's relevant security mechanisms (File Quarantine, Gatekeeper, and Notarization requirements) …even on a fully patched M1 macOS system.
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'Armed with such a capability macOS malware authors could (and are) returning to their proven methods of targeting and infecting macOS users.'
Mac security firm Jamf said in a separate blog post that it had located Shlayer malware already exploiting the bug.
'To make the situation more urgent, the Jamf Protect detections team observed this exploit being used in the wild by a variant of the Shlayer adware dropper,' it said.
'The variant has been repackaged to use a format necessary for carrying out the Gatekeeper bypass vulnerability.
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'The Jamf Protect detection team identified samples found to be abusing this vulnerability as early as January 9, 2021.
'Shlayer continues to reintroduce itself with innovative ways to infect macOS-based systems.'
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Scary challenge mac os. Jamf said that when malware exploiting the bug is launched on computers running Big Sur 11.3, 'the user will see a pop-up message stating that the software ‘cannot be opened because the developer cannot be identified.'
'Since the malicious application is not notarised or signed with a valid developer's certificate, the message will prompt the user to eject the mounted DMG containing the app bundle,' it added.
Owens praised Apple's quick response to patching the flaw. Balldodge mac os.
'Kudos to Apple for rolling out a fix in Big Sur 11.3 beta 6 literally five days after I reported to them,' he wrote.
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'The product security team at Apple was very responsive anytime I reached out with an inquiry.
'I highly encourage you to update to Big Sur 11.3 soonest, as the fix has been applied .. so that Gatekeeper now properly blocks this payload on macOS 11.3.'